Human Neuregulin 4 (NRG4) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits NRG4
proveedor
Abbexareference
abx152489Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Neuregulin 4 (NRG4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neuregulin 4 (NRG4) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Neuregulin 4 (NRG4)No significant cross-reactivity or interference between Neuregulin 4 (NRG4) and analogues was observed.
Background
Neuregulin 4 (NRG4) is a member of the neuregulin family, which consists of growth factors that play critical roles in cell signaling, development, and homeostasis. NRG4 primarily acts through the ErbB family of receptor tyrosine kinases, notably interacting with ErbB4 to initiate downstream signaling pathways. This signaling is involved in a variety of physiological processes, including metabolism, tissue repair, and the regulation of energy balance. Research suggests that NRG4 may have protective roles in metabolic disorders, such as obesity and type 2 diabetes, by modulating insulin sensitivity and inflammatory responses in key tissues like the liver and adipose tissue. Additionally, NRG4's role in neuronal and cardiac development has also been noted, highlighting its importance across diverse biological systems. Further exploration of NRG4's signaling mechanisms may provide valuable insights into therapeutic strategies for metabolic and neurodegenerative diseases.
Características del producto
category
ELISA Kits
immunogen target
Neuregulin 4 (NRG4)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
HRG4,Pro-NRG4,Pro-neuregulin-4 membrane-bound isoform
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
NRG4
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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