Human Neural Cell Adhesion Molecule 2 (NCAM2) ELISA Kit

Este producto es parte de NCAM - neural cell adhesion molecule
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643.5€ (96 tests)

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935106861
info@markelab.com
name
Human Neural Cell Adhesion Molecule 2 (NCAM2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx152462
tested applications
ELISA

Description

Human Neural Cell Adhesion Molecule 2 (NCAM2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neural Cell Adhesion Molecule 2 (NCAM2) concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Neural Cell Adhesion Molecule 2 (NCAM2)

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Neural Cell Adhesion Molecule 2 (NCAM2)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
NCAM21,N-CAM-2
Background
Elisa kits for NCAM2
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Neural Cell Adhesion Molecule 2 (NCAM2), also known as OCAM (Olfactory Cell Adhesion Molecule), is another member of the immunoglobulin (Ig) superfamily that mediates cell adhesion and neuronal connectivity. NCAM2 shares structural similarities with NCAM1, including five Ig-like domains and two fibronectin type III domains in its extracellular region. However, NCAM2 has distinct roles in the olfactory system and brain development. It is highly expressed in olfactory neurons, where it regulates axon guidance and synaptic targeting. NCAM2 is crucial for neuronal differentiation and the establishment of specific neural circuits, particularly in the hippocampus and olfactory bulb. It mediates homophilic binding (interaction with identical molecules) to promote cell adhesion and structural organization. In the brain, NCAM2 is essential for the maintenance of synaptic connections and proper cortical layering.

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