Human NCAM2 (Neural cell adhesion molecule 2) ELISA Kit

Este producto es parte de NCAM - neural cell adhesion molecule
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935106861
info@markelab.com
name
Human NCAM2 (Neural cell adhesion molecule 2) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH1411
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
O15394
Alias
NCAM21,N-CAM-2
Background
Elisa kits for NCAM2
Status
RUO

Neural Cell Adhesion Molecule 2 (NCAM2), also known as OCAM (Olfactory Cell Adhesion Molecule), is another member of the immunoglobulin (Ig) superfamily that mediates cell adhesion and neuronal connectivity. NCAM2 shares structural similarities with NCAM1, including five Ig-like domains and two fibronectin type III domains in its extracellular region. However, NCAM2 has distinct roles in the olfactory system and brain development. It is highly expressed in olfactory neurons, where it regulates axon guidance and synaptic targeting. NCAM2 is crucial for neuronal differentiation and the establishment of specific neural circuits, particularly in the hippocampus and olfactory bulb. It mediates homophilic binding (interaction with identical molecules) to promote cell adhesion and structural organization. In the brain, NCAM2 is essential for the maintenance of synaptic connections and proper cortical layering.

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