Human Natural Killer Cell Receptor 2B4 (CD244) ELISA Kit
![Human Natural Killer Cell Receptor 2B4 (CD244) ELISA Kit](/_next/image?url=https%3A%2F%2Fmarkelab.com%2Fpublic-files%2Fimages%2FELISA-box.webp&w=3840&q=75)
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits CD244
proveedor
Abbexareference
abx386387Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Natural Killer Cell Receptor 2B4 (CD244) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Natural Killer Cell Receptor 2B4 (CD244) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CD244, also known as 2B4, is a receptor primarily expressed on natural killer (NK) cells and subsets of T cells. CD244 is encoded by the CD244 gene and belongs to the Signaling Lymphocyte Activation Molecule (SLAM) family within the immunoglobulin superfamily. This receptor plays a key role in immune regulation, functioning as a modulator of cytotoxic responses against infected or malignant cells. CD244 interacts with its ligand, CD48, a widely expressed protein found on hematopoietic cells, allowing it to mediate immune surveillance and inflammatory responses. CD244 has gained significant attention due to its dual role as an activating and inhibitory receptor on immune cells, where its function depends largely on the cellular context and specific signal cascades involved. Unlike many receptors that have a straightforward activating or inhibitory role, CD244 is unique in its ability to modulate immune responses through varying interactions with different proteins in NK cells and T cells.
Características del producto
category
ELISA Kits
immunogen target
Natural Killer Cell Receptor 2B4 (CD244)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
Natural killer cell receptor 2B4,2B4,NAIL,Nmrk,NKR2B4,SLAMF4,NK cell activation-inducing ligand,SLAM family member 4,Signaling lymphocytic activation molecule 4
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
CD244
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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