Human Natural Killer Cell Receptor 2B4 (CD244) ELISA Kit

Este producto es parte de CD244 - CD244 molecule
Human Natural Killer Cell Receptor 2B4 (CD244) ELISA Kit
715€ (96 tests)

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Name
Human Natural Killer Cell Receptor 2B4 (CD244) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx386387
Tested Applications
ELISA

Description

Human Natural Killer Cell Receptor 2B4 (CD244) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Natural Killer Cell Receptor 2B4 (CD244) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Natural Killer Cell Receptor 2B4 (CD244)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9BZW8
Gene ID
51744
OMIM
605554
Alias
Natural killer cell receptor 2B4,2B4,NAIL,Nmrk,NKR2B4,SLAMF4,NK cell activation-inducing ligand,SLAM family member 4,Signaling lymphocytic activation molecule 4
Background
Elisa Kits for: CD244
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

CD244, also known as 2B4, is a receptor primarily expressed on natural killer (NK) cells and subsets of T cells. CD244 is encoded by the CD244 gene and belongs to the Signaling Lymphocyte Activation Molecule (SLAM) family within the immunoglobulin superfamily. This receptor plays a key role in immune regulation, functioning as a modulator of cytotoxic responses against infected or malignant cells. CD244 interacts with its ligand, CD48, a widely expressed protein found on hematopoietic cells, allowing it to mediate immune surveillance and inflammatory responses. CD244 has gained significant attention due to its dual role as an activating and inhibitory receptor on immune cells, where its function depends largely on the cellular context and specific signal cascades involved. Unlike many receptors that have a straightforward activating or inhibitory role, CD244 is unique in its ability to modulate immune responses through varying interactions with different proteins in NK cells and T cells.

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