Human Natural Cytotoxicity Triggering Receptor 3 (NCR3) Protein
273€ (10 µg)
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name
Human Natural Cytotoxicity Triggering Receptor 3 (NCR3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690099
tested applications
SDS-PAGE
Description
Human NCR3 Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Natural Cytotoxicity Triggering Receptor 3 is produced by our Mammalian expression system and the target gene encoding Leu19-Thr138 is expressed with a 6His tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | NCR3 |
| Host | Human |
| Origin | Human |
| Observed MW | Molecular Weight: 12.8 kDa Sequence Fragment: Leu19-Thr138 Tag: C-terminal 6 His tag |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM PB, 150mM NaCl, pH 7.2. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| UniProt ID | O14931 |
| Alias | Activating natural killer receptor p30,1C7,MALS,CD337,LY117,NKp30,Natural killer cell p30-related protein |
| Background | Protein NCR3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Natural Cytotoxicity Triggering Receptor 3 (NCR3), also known as NKp30, is a critical receptor for natural killer (NK) cell activation and functions as part of the body’s innate immune response. NK cells are lymphocytes specialized in identifying and killing abnormal cells, such as those infected by viruses or transformed into cancer cells. Unlike T cells and B cells, which rely on antigen specificity, NK cells use a variety of activating receptors, including NCR3, to recognize stressed or infected cells. NCR3, part of the NCR family (alongside NCR1 and NCR2), plays a vital role in immune surveillance by mediating NK cell cytotoxicity and cytokine production in response to cellular stress signals. NCR3’s activation allows NK cells to promptly respond to potential threats without prior sensitization. NCR3 is distinct among the NCRs in its broader expression across both innate and adaptive immune cells, and its activity has been shown to influence adaptive immunity. NCR3 is found not only on NK cells but also on certain subtypes of T cells and other immune cells in specific conditions, amplifying its potential for immune modulation.
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