Human Natural Cytotoxicity Triggering Receptor 2 (NCR2) ELISA Kit

715€ (96 tests)
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name
Human Natural Cytotoxicity Triggering Receptor 2 (NCR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx257676
tested applications
ELISA
Description
Human Natural Cytotoxicity Triggering Receptor 2 (NCR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Natural Cytotoxicity Triggering Receptor 2 (NCR2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | Natural Cytotoxicity Triggering Receptor 2 (NCR2) |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Test Range | 0.156 ng/ml - 10 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | O95944 |
Alias | Lymphocyte antigen 95 homolog,LY95,CD336,NKP44,NK-p44,NK cell-activating receptor,Natural killer cell p44-related protein |
Background | Elisa kits for NCR2 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Natural Cytotoxicity Triggering Receptor 2 (NCR2), also known as NKp44, is an activating receptor on the surface of natural killer (NK) cells. NK cells are crucial components of the innate immune system, specializing in the recognition and destruction of abnormal cells, including tumor cells and virus-infected cells. Unlike other immune cells, such as T and B lymphocytes, which rely on antigen-specific receptors, NK cells use NCR2 and other activating receptors to identify stressed, infected, or transformed cells without prior sensitization. This unique ability enables NK cells to mount a rapid immune response. NCR2 is part of the NCR family, which also includes NCR1 (NKp46) and NCR3 (NKp30). These receptors, along with others like NKG2D, enable NK cells to recognize target cells that exhibit ligands associated with cellular stress or infection. NCR2 is specifically expressed on activated NK cells and is involved in both direct cytotoxicity and the secretion of cytokines and chemokines, amplifying the immune response. NCR2 plays an essential role in immune surveillance, contributing to the early detection and elimination of tumors and infection.
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