Human Myosin VIIB (MYO7B) Protein

Background

Myosin VIIB (MYO7B) is a motor protein from the myosin family, which is involved in ATP-dependent cellular movements Myosin VIIB, like other myosins, moves along actin filaments, converting chemical energy into mechanical work This motor protein is crucial for cellular processes such as vesicular transport, endocytosis, and cell migration MYO7B plays a specific role in the auditory and visual systems, where it is involved in the function of sensory cells, including the hair cells of the inner ear and photoreceptors in the retina In the inner ear, MYO7B helps maintain the structure and function of hair cells, which are responsible for detecting sound vibrations and balancing signals Disruption in MYO7B function leads to hearing loss and progressive blindness, as seen in Usher syndrome type 2, where both deafness and vision impairment occur due to defects in inner ear and retinal cells