Human Myeloid Cell Surface Antigen CD33 (CD33) Protein
247€ (10 µg)
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935106861
info@markelab.com
name
Human Myeloid Cell Surface Antigen CD33 (CD33) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691369
tested applications
SDS-PAGE
Description
Human Sialic Acid Binding Ig-Like Lectin 3 Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Sialic Acid Binding Ig-like Lectin 3 is produced by our Mammalian expression system and the target gene encoding Asp18-His259 is expressed with a Fc, 6His tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Sialic Acid Binding Ig-Like Lectin 3 |
| Host | Human |
| Origin | Human |
| Observed MW | Molecular Weight: 55 kDa Sequence Fragment: Asp18-His259 Tag: C-terminal Fc tag and 6 His tag |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM PB, 150mM NaCl, 2mM EDTA, pH 7.2. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| UniProt ID | P20138 |
| Alias | p67,SIGLEC3,SIGLEC-3,CD33rSiglec,Sialic acid-binding Ig-like lectin 3,Myeloid cell surface antigen CD33 |
| Background | Protein CD33 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD33, also known as Siglec-3 (Sialic acid-binding Ig-like lectin 3), is a transmembrane receptor expressed primarily on cells of myeloid lineage. It belongs to the immunoglobulin (Ig) superfamily and plays a significant role in the regulation of innate immunity. CD33 was first identified in the late 1980s as a marker on acute myeloid leukemia (AML) cells, making it a focal point for research in hematological malignancies. This glycoprotein is encoded by the CD33 gene located on chromosome 19q13.3. CD33 is involved in cellular signaling processes that modulate immune cell function and survival.
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