Human Myeloid Cell Surface Antigen CD33 (CD33) Protein
234€ (10 µg)
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Name
Human Myeloid Cell Surface Antigen CD33 (CD33) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx691369
Tested Applications
SDS-PAGE
Description
Myeloid Cell Surface Antigen CD33 (CD33) protein is a recombinant Human protein expressed in HEK293 cells.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Myeloid Cell Surface Antigen CD33 (CD33) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Asp18-His259 Tag: C-terminal Fc tag and 6 His tag |
| Origin | Human |
| Observed MW | Calculated MW: 55.0 kDa Observed MW (SDS-PAGE): 80 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Purification | 0.2 µm filtered prior to lyophilization. |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM PBS, 150 mM NaCl, 2 mM EDTA, pH 7.2, containing 5%-8% Trehalose, Mannitol and 0.01% Tween 80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | P20138 |
| Gene ID | 945 |
| OMIM | 159590 |
| Alias | p67,SIGLEC3,SIGLEC-3,CD33rSiglec,Sialic acid-binding Ig-like lectin 3,Myeloid cell surface antigen CD33 |
| Background | Protein CD33 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in sterile H2O to prepare a stock solution of concentration 0.25 mg/ml. Do not vortex. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Background
CD33, also known as Siglec-3 (Sialic acid-binding Ig-like lectin 3), is a transmembrane receptor expressed primarily on cells of myeloid lineage. It belongs to the immunoglobulin (Ig) superfamily and plays a significant role in the regulation of innate immunity. CD33 was first identified in the late 1980s as a marker on acute myeloid leukemia (AML) cells, making it a focal point for research in hematological malignancies. This glycoprotein is encoded by the CD33 gene located on chromosome 19q13.3. CD33 is involved in cellular signaling processes that modulate immune cell function and survival.
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