Human Myc Proto-Oncogene Protein (MYC) ELISA Kit
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935106861
info@markelab.com
Precio
546€ (96 tests)
Elisa kits for MYC
proveedor
Abbexareference
abx252232Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Myc Proto-Oncogene Protein (MYC) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human c-myc Oncogene Product concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
The MYC proto-oncogene encodes a basic helix-loop-helix (bHLH) transcription factor that is central to regulating cell growth, proliferation, and metabolism. It acts as a master regulator by binding to E-box sequences within the genome to control the transcription of numerous genes involved in key cellular processes, such as ribosome biogenesis, cell cycle progression, and apoptosis. Dysregulation of MYC, often through overexpression or amplification, is a hallmark of many cancers, including Burkitt lymphoma and various solid tumors. This dysregulation promotes uncontrolled cell proliferation and impairs apoptosis, contributing to tumorigenesis. Additionally, MYC interacts with multiple co-factors and chromatin-modifying complexes, further amplifying its impact on the epigenetic landscape. Given its critical role in oncogenesis, MYC is extensively studied as a therapeutic target, with ongoing efforts to develop strategies to inhibit its activity or downstream pathways to treat MYC-driven malignancies. Its widespread effects on cellular physiology underscore its importance in both normal development and disease.
Características del producto
category
ELISA Kits
immunogen target
Myc Proto-Oncogene Protein (MYC)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
MRTL,MYCC,c-Myc,bHLHe39,Transcription factor p64,Proto-oncogene c-Myc,Class E basic helix-loop-helix protein 39
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
MYC
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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