935106861
info@markelab.com
Precio
812.5€ (96 tests)
Human ATP Binding Cassette Transporter C4 (ABCC4) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Human ATP Binding Cassette Transporter C4 (ABCC4) CLIA Kit es un kit CLIA tipo Sandwich para su uso con homogeneizados de tejido, lisados de células y otros fluidos biológicos.
ABCC4, also known as multidrug resistance-associated protein 4 (MRP4), is an ATP-binding cassette transporter expressed in various tissues, including the liver, kidneys, and endothelial cells of the blood-brain barrier. It exports a wide range of substrates, including cyclic nucleotides, prostaglandins, antiviral drugs, and chemotherapeutic agents, from cells. ABCC4’s activity plays a critical role in cellular signaling by regulating intracellular levels of cyclic AMP and GMP. It is also involved in drug resistance, where its overexpression limits the intracellular accumulation of therapeutic agents. ABCC4 is upregulated in response to oxidative stress and inflammation, highlighting its role in protecting cells from toxic insults. Its diverse substrate specificity and involvement in drug efflux make ABCC4 a significant target in pharmacological research and disease management.
CLIA Kits
Multidrug resistance-associated protein 4 (ABCC4)
Human
27.4 pg/ml - 20000 pg/ml
< 9.7 pg/ml
Sandwich
Quantitative
Lyophilized
Chemiluminescent
Tissue homogenates, cell lysates and other biological fluids.
96 tests
5 × 96 tests
10 × 96 tests
MOAT-B,MOATB,MRP4,Multidrug resistance-associated protein 4
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
ABCC4
No
El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.
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