Human Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) Protein

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Description
Human Mitogen-Activated Protein Kinase Kinase 3 Protein is a recombinant protein kinases.
Documents del producto
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) |
Host | E. coli |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Origin | Human |
Expression | Recombinant |
Purity | > 90% (SDS-PAGE) |
Size 1 | 1 µg |
Size 2 | 5 µg |
Size 3 | 50 µg |
Form | Liquid |
Tested Applications | SDS-PAGE |
Availability | Shipped within 5-10 working days. |
Storage | Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P46734 |
Background | Protein MAP2K3 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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MAP2K3 (pS189) Antibody is a Rabbit Polyclonal antibody against MAP2K3 (pS189). MKK3 and MKK6 are two closely related dual-specificity protein kinases that activate p38 MAP kinase. MKK3 and MKK6 both phosphorylate and activate p38 MAP kinase at its activation site, Thr-Gly-Tyr, but do not phosphorylate or activate Erk1/2 or SAPK/JNK. Phosphorylation of p38 MAP kinase dramatically stimulates its ability to phosphorylate protein substrates such as ATF-2 and Elk-1. MKK3 and MKK6 are both activated by different forms of cellular stress and inflammatory cytokines. Activation of MKK3 and MKK6 occurs through phosphorylation of Ser189 and Thr193 on MKK3 and Ser207 and Thr211 on MKK6.
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