Human Microtubule Associated Protein 2 (MAP2) CLIA Kit

Este producto es parte de MAP2 - microtubule associated protein 2
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643.5€ (96 tests)

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935106861
info@markelab.com
name
Human Microtubule Associated Protein 2 (MAP2) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx197289
tested applications
CLIA

Description

Human Microtubule Associated Protein 2 (MAP-2) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Microtubule Associated Protein 2 (MAP-2).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
CLIA Kits
Immunogen Target
Microtubule Associated Protein 2 (MAP2)
Reactivity
Human
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
62.5 pg/ml - 4000 pg/ml
Sensitivity
37.5 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
 Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
MAP-2,MAP2A,MAP2B,MAP2C
Background
CLIA Kits MAP2
Status
RUO
Note
The validity for this kit is 6 months.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Microtubule-associated protein 2 (MAP2) is a protein primarily found in neurons, where it plays a crucial role in stabilizing microtubules, maintaining cell shape, and supporting dendritic development MAP2 is part of a family of microtubule-associated proteins that bind to microtubules and regulate their stability, thereby contributing to the structural integrity of the cytoskeleton In neurons, MAP2 is essential for dendritic growth and synaptic plasticity, as it helps organize microtubules that extend into dendritic spines, the sites of synaptic connections and communication Dysregulation or loss of MAP2 function is associated with neurodegenerative diseases such as Alzheimer's disease and tauopathies, where disrupted microtubule stability leads to impaired neuronal function and neurofibrillary tangles MAP2 also serves as a marker for dendritic structures in neurons and is important for maintaining the organization of the central nervous system during development and in response to injury

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