Human Meteorin Like Protein (METRNL) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Human Meteorin Like Protein (METRNL) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx251722
tested applications
ELISA
Description
Human Meteorin Like Protein (METRNL) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Meteorin Like Protein concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Meteorin Like Protein (METRNL) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 1.56 ng/ml - 100 ng/ml |
| Sensitivity | < 0.64 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | Subfatin |
| Background | Elisa Kits for: METRNL |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Meteorin-like protein (METRNL) shares structural similarity with Meteorin and is secreted primarily by adipose tissue and muscle, where it plays a role in energy metabolism and inflammation. METRNL has been identified as a myokine and adipokine that promotes thermogenesis in beige adipocytes by inducing the expression of uncoupling protein 1 (UCP1) and activating macrophages to secrete IL-4 and IL-13. This process enhances energy expenditure and improves metabolic health, making METRNL a potential therapeutic target for obesity and metabolic syndrome. Additionally, METRNL exhibits anti-inflammatory properties, modulating immune responses in adipose tissue and skeletal muscle during exercise or metabolic stress. Recent research indicates its involvement in tissue repair and regeneration, particularly in response to injury or disease, through its interaction with signaling pathways like AMPK and MAPK.
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