Human Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody Pair

Product Graph
1040€ (1 Pair)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx378397
tested applications
ELISA

Description

Human Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody Pair for use in Sandwich ELISA assay development.
Detection: 50 µl
Capture: 100 µg

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Antibody Pairs
Immunogen Target
Human Macrophage Inflammatory Protein 1 Beta (MIP1b)
Host
Capture Host: Goat
Detection Host: Goat
Reactivity
Human
Assay Data
Sandwich
Assay Type
Capture antibody concentration: 0.5 mg/ml
Recommended Dilution
ELISA (Capture Antibody) 0.5-4 μg/ml, ELISA (Detection Antibody) 1/1000 - 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Capture Clonality: Polyclonal
Detection Clonality: Polyclonal
Conjugation
Biotin
Purification
Purified by antigen affinity chromatography.
Size 1
1 Pair
Form
Liquid
Tested Applications
ELISA
Buffer
Capture antibody: PBS, pH 7.4, containing 0.04% Proclin-300, 50% glycerol.<br>Detection antibody: PBS containing 0.04% Proclin-300.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C for up to 1 year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P13236
Background
Antibody pair for MIP1b
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Related Products

abx001404

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

MIP1b Antibody is a Rabbit Polyclonal antibody against MIP1b. Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine family exhibit 20 to 50% homology in their predicted amino acid sequences and are divided into four subfamilies. In C-C (or b) subfamily, the first two cysteines are adjacent. C-C chemokines are chemoattractants and activators for monocytes and T cells. C-C subfamily members include macrophage inflammatory protein (MIP)-1å, MIP-1∫, MIP-2, MIP-3å, MIP-3∫, MIP-4, HCC-1, MIP-5 (or HCC-2), RANTES, MCP-1/2/3 (and the murine homologs JE and MARC), I-309, murine C10 and TCA3. Research has shown that MIP-1∫ is more selective than MIP-1å, primarily attracting CD4+ T lymphocytes, with a preference for T cells of the naive phenotype. MIP-1å is a more potent lymphocyte chemoattractant than MIP-1∫ and exhibits a broader range of chemoattractant specificities. It has been suggested that CD8+ T lymphocytes are involved in the control of HIV infection in vivo by the release of HIV-suppressive factors (HIV-SF). MIP-1å has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1∫ and RANTES. Recombinant human MIP-1å acts as an inhibitor of different strains of HIV-1, HIV-2 and SIV infection in a dose-dependent manner.

Ver Producto
abx025005

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. This protein is similar to MIP1b which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals; most individuals have 1-5 copies in the diploid genome, although rare individuals do not contain this gene at all. The human genome reference assembly contains two copies of this gene. This record represents the more centromeric gene. [provided by RefSeq].

Ver Producto
abx067890

Cow Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein

Recombinant MIP1b (MIP1b) is a recombinant Cow protein produced in a Prokaryotic expression system (E. coli).

Ver Producto