Human Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Cell ELISA Kit
513.5€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Cell ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx595153
Tested Applications
ELISA
Description
CSFR Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Tested Applications | ELISA |
| Availability | Shipped within 1-2 weeks. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P07333 |
| Gene ID | 1436 |
| OMIM | 164770 |
| Alias | Macrophage colony-stimulating factor 1 receptor,FMS,CSFR,FIM2,GPSC,HDLS,C-FMS,CD115,HDLS1,CSF-1R,BANDDOS,M-CSF-R,Proto-oncogene c-Fms,CSF-1 receptor |
| Background | Elisa Kits for: CSF1R |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Background
The Colony Stimulating Factor 1 Receptor (CSF1R), also known as macrophage colony-stimulating factor receptor or CD115, is a cell surface receptor that primarily regulates the survival, proliferation, and differentiation of monocytes, macrophages, and osteoclasts. CSF1R is a transmembrane protein belonging to the receptor tyrosine kinase (RTK) family and is activated by binding to its primary ligand, colony-stimulating factor 1 (CSF1), as well as the alternative ligand interleukin-34 (IL-34). This receptor is essential for various immune functions and bone metabolism, primarily because of its role in maintaining and activating macrophage populations. The CSF1R gene is located on chromosome 5 (5q32) and encodes a protein that is essential in regulating macrophage differentiation, survival, and function. CSF1R signaling influences immune response, inflammation, tissue homeostasis, and bone remodeling. Dysregulation of CSF1R or its signaling pathways has been associated with pathological conditions such as inflammatory diseases, cancer, and neurodegenerative disorders. Furthermore, mutations in CSF1R have been implicated in a group of disorders characterized by leukoencephalopathy and early-onset neurodegeneration.
Productos relacionados
Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody
CSF1R Antibody is a Rabbit Polyclonal antibody against CSF1R. The protein encoded by this gene is the receptor for colon…
Ver producto
Macrophage Colony-Stimulating Factor 1 Receptor Phospho-Tyr561 (CSF1R pY561) Antibody
Rabbit polyclonal antibody against CSFR protein. Immunogen region is Internal. Specificity is as follows for the reactiv…
Ver producto
Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody
CSF1R Antibody is a Mouse Monoclonal against CSF1R.…
Ver producto