Human Lysosomal Associated Membrane Protein 3 (LAMP3) Protein

Pida mas información
935106861
info@markelab.com
Precio
221€ (10 µg)
Protein LAMP3
proveedor
Abbexareference
abx168716Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human LAMP3 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
Lysosome-associated membrane glycoprotein 3 (LAMP3), also known as DC-LAMP, is a lysosomal membrane protein predominantly expressed in dendritic cells and other immune cells, where it plays a critical role in antigen processing and presentation LAMP3 expression increases during dendritic cell maturation, facilitating the regulation of lysosomal function and endosomal trafficking It is also involved in lysosome-mediated autophagy and immune responses by regulating cellular degradation pathways Dysregulation of LAMP3 has been linked to cancer progression and metastasis, particularly in breast, cervical, and lung cancers, where its overexpression promotes tumor cell survival and invasion through altered lysosomal activity Additionally, LAMP3 has been implicated in hypoxia response pathways, contributing to cellular adaptation to low oxygen environments Emerging studies highlight its role in viral infections, where it can affect viral replication and host immune response, making LAMP3 a potential biomarker for immune regulation and cancer prognosis
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Lysosomal Associated Membrane Protein 3 (LAMP3)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 21.5 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser222-Thr381 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
LAMP3
dry ice
No
availability
Shipped within 5-7 working days.
alias
CD208,DC LAMP,DC-LAMP,DCLAMP,LAMP,LAMP-3,TSC403,DC-lysosome-associated membrane glycoprotein
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
anti- LAMP3 antibody

proveedor
FineTestreference
FNab04687Tested Applications
ELISA, WB, IHCreactivity
human,mouse,ratstatus
RUOclonality
polyclonalMay play a role in dendritic cell function and in adaptive immunity.
Precio a consultar
Ver másRecombinant Human CD208

proveedor
FineTestreference
P1677Tested Applications
Western Blot, ELISAstatus
RUOPrecio a consultar
Ver másLysosomal Associated Membrane Protein 3 (LAMP3) Antibody

proveedor
Abbexareference
abx002126Tested Applications
IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalLAMP3 Antibody is a Rabbit Polyclonal antibody against LAMP3. Lysosome-associated membrane glycoprotein 3 is a protein t...
312€ (60 µl)
Ver más