Human Lysophosphatidic acid receptor 5 (LPAR5) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Lysophosphatidic acid receptor 5 (LPAR5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531254
tested applications
ELISA
Description
Human Lysophosphatidic acid receptor 5 (LPAR5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Lysophosphatidic acid receptor 5 (LPAR5) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Lysophosphatidic acid receptor 5 (LPAR5) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9H1C0 |
| Alias | LPAR5,GPR92,GPR93,KPG_010,LPA5,G protein-coupled receptor 92 |
| Background | Elisa kits for LPAR5 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LPAR5 is a G protein-coupled receptor activated by lysophosphatidic acid (LPA), primarily coupling to G12/13 and Gq proteins. It is expressed in the gastrointestinal tract, immune cells, and sensory neurons, where it regulates cellular responses such as migration, cytoskeletal reorganization, and inflammatory signaling. LPAR5 plays a significant role in immune modulation and inflammatory responses by mediating immune cell trafficking and cytokine release. In the gastrointestinal tract, LPAR5 regulates intestinal epithelial cell homeostasis and motility, making it relevant in gut inflammation and tissue repair. Additionally, LPAR5 is implicated in neuropathic pain, where its activation sensitizes sensory neurons, contributing to pain perception. Dysregulation of LPAR5 signaling has been linked to inflammatory diseases, neuropathic pain, and cancer progression, where it enhances tumor cell migration and survival. LPAR5 antagonists are under investigation for therapeutic use in conditions such as inflammatory bowel disease, neuropathic pain, and cancer metastasis, highlighting its potential as a target for immune and inflammatory regulation.
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