Human Lys-63-Specific Deubiquitinase BRCC36 (BRCC3) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for BRCC3
proveedor
Abbexareference
abx050248Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Lys-63-Specific Deubiquitinase BRCC36 (BRCC3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Lys-63-Specific Deubiquitinase BRCC36 (BRCC3) concentrations in tissue homogenates, cell lysates and other biological fluids. This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5.
Características del producto
category
ELISA Kits
immunogen target
Lys-63-Specific Deubiquitinase BRCC36 (BRCC3)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
BRCC3
dry ice
No
uniprot id
NCBI accession
NP_001018065.1, NM_001018055.2, NP_001229569.1, NM_001242640.1, NP_077308.1, NM_024332.3
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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