Human Lymphocyte Antigen 9 (LY9) CLIA Kit

Este producto es parte de LY9 - lymphocyte antigen 9
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845€ (96 tests)

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935106861
info@markelab.com
name
Human Lymphocyte Antigen 9 (LY9) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx492981
tested applications
CLIA

Description

Human Lymphocyte Antigen 9 (LY9) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryCLIA Kits
Immunogen TargetLymphocyte Antigen 9 (LY9)
ReactivityHuman
Detection MethodChemiluminescent
Assay DataQuantitative
Assay TypeSandwich
Test Range0.312 ng/ml - 20 ng/ml
Sensitivity< 0.128 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsCLIA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-20 working days.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
AliasT-lymphocyte surface antigen Ly-9,hly, mLY9,CD229,SLAMF3,Cell surface molecule Ly-9,SLAM family member 3
BackgroundCLIA Kits LY9
StatusRUO
NoteThe validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Lymphocyte antigen 9 (LY9), also known as SLAMF3 (Signaling Lymphocytic Activation Molecule Family Member 3), is a transmembrane glycoprotein and member of the immunoglobulin (Ig) superfamily. This molecule is part of the broader SLAM family, a set of proteins primarily expressed on immune cells. LY9, like other SLAM family members, plays a key role in immune cell signaling, cell-to-cell interactions, and immunoregulation, specifically in adaptive immunity. This protein is highly expressed on lymphocytes, particularly T cells and natural killer (NK) cells, and it is involved in mediating various immune responses by interacting with other immune cells. LY9 participates in homotypic interactions, meaning it binds to another LY9 molecule on adjacent cells, facilitating immune cell communication and signaling. Its expression is primarily associated with lymphoid tissues, but it is also present on other immune cells, where it regulates responses by activating intracellular signaling cascades. Studies show that LY9 contributes to immune regulation by affecting processes such as cytokine secretion, cytotoxicity, and immune cell differentiation. Given its involvement in immune signaling, LY9 is being investigated as a therapeutic target in conditions where immune regulation is disrupted, including autoimmune diseases, cancers, and immunodeficiencies.

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