Human Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits FCGR2C
proveedor
Abbexareference
abx556342Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
FCGR2C (Fc gamma receptor IIc), also known as CD32C, is a member of the Fc gamma receptor (FcγR) family, which binds to the Fc portion of immunoglobulin G (IgG). This receptor is of significant interest due to its functional variability and implications in immune regulation. FCGR2C is a low-affinity receptor and, unlike other Fc gamma receptors, is expressed in only a subset of immune cells due to complex regulation at the genetic and transcriptional levels. FCGR2C is unique because it arises from a combination of genetic recombination between its closely related genes, FCGR2A (an activating receptor) and FCGR2B (an inhibitory receptor), resulting in hybrid characteristics. The FCGR2C gene is located on chromosome 1q23, a region where other Fcγ receptor family members are also found. This region is known for its genetic variability, contributing to differential expression of these receptors in the population. While FCGR2C was originally thought to be a pseudogene in many individuals, subsequent studies revealed that a significant proportion of the population expresses a functional receptor due to specific genetic recombination events.
Características del producto
category
ELISA Kits
immunogen target
Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
CD32,FCG2,CD32C,CDW32,IGFR2,FCRIIC,FcgammaRIIc,Low affinity immunoglobulin gamma Fc region receptor II-c,IgG Fc receptor II-c,CDw32,Fc-gamma RII-c,FcRII-c
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
FCGR2C
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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