Human Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx556342
tested applications
ELISA
Description
Human Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P31995 |
| Gene ID | 9103 |
| OMIM | 612169 |
| Alias | CD32,FCG2,CD32C,CDW32,IGFR2,FCRIIC,FcgammaRIIc,Low affinity immunoglobulin gamma Fc region receptor II-c,IgG Fc receptor II-c,CDw32,Fc-gamma RII-c,FcRII-c |
| Background | Elisa kits for FCGR2C |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
FCGR2C (Fc gamma receptor IIc), also known as CD32C, is a member of the Fc gamma receptor (FcγR) family, which binds to the Fc portion of immunoglobulin G (IgG). This receptor is of significant interest due to its functional variability and implications in immune regulation. FCGR2C is a low-affinity receptor and, unlike other Fc gamma receptors, is expressed in only a subset of immune cells due to complex regulation at the genetic and transcriptional levels. FCGR2C is unique because it arises from a combination of genetic recombination between its closely related genes, FCGR2A (an activating receptor) and FCGR2B (an inhibitory receptor), resulting in hybrid characteristics. The FCGR2C gene is located on chromosome 1q23, a region where other Fcγ receptor family members are also found. This region is known for its genetic variability, contributing to differential expression of these receptors in the population. While FCGR2C was originally thought to be a pseudogene in many individuals, subsequent studies revealed that a significant proportion of the population expresses a functional receptor due to specific genetic recombination events.
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