Human Liver Carboxylesterase 1 (CES1) Enzyme (Active)
234€ (2 µg)
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name
Human Liver Carboxylesterase 1 (CES1) Enzyme (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx074308
tested applications
SDS-PAGE
Description
Human Liver Carboxylesterase 1 Protein is a recombinant enzyme produced in Sf9 insect cells. It contains a single, glycosylated polypeptide chain containing 559 amino acids (19-568 AA) and is fused to a C-terminal His tag.
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Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Liver Carboxylesterase 1 (CES1) |
| Host | Insect |
| Assay Type | Activity: Active Sequence Fragment: 19-568 AA. Tag: C-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | 61.7 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Purification | Purified by proprietary chromatographic techniques. <br> Sterile Filtered. |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Buffer | 25 mM Sodium Acetate, pH 4.0, containing 10% glycerol, 0.1 M NaCl and 0.1 mM PMSF. |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4°C if the entire vial will be used within 4 weeks. Store at -20 °C for long-term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P23141 |
| Background | Protein CES1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Concentration: 0.5 mg/ml |
Descripción
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This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
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