Human Limbic System-Associated Membrane Protein (LSAMP) Protein

Background

Limbic System Associated Membrane Protein (LSAMP) is a critical cell adhesion molecule that plays a vital role in the limbic system, a set of brain structures involved in emotion, behavior, long-term memory, and olfaction. LSAMP is part of the immunoglobulin superfamily of cell adhesion molecules (IgCAMs) and is implicated in neural development and synaptic plasticity. This protein is particularly expressed in regions of the brain such as the hippocampus, amygdala, and cingulate cortex, which are all key components of the limbic system. Research into LSAMP has highlighted its importance in the establishment and maintenance of neural networks and its potential involvement in various neuropsychiatric conditions.