Human Leukocyte Immunoglobulin Like Receptor Subfamily B Member 5 (LILRB5) ELISA Kit

Este producto es parte de LILRB5 - leukocyte immunoglobulin like receptor B5
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Leukocyte Immunoglobulin Like Receptor Subfamily B Member 5 (LILRB5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx388275
tested applications
ELISA

Description

Human Leukocyte Immunoglobulin Like Receptor Subfamily B Member 5 (LILRB5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human LILRB5 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetLeukocyte Immunoglobulin Like Receptor Subfamily B Member 5 (LILRB5)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range0.313 ng/ml - 20 ng/ml
Sensitivity< 0.188 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-12 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDO75023
Gene ID10990
OMIM604814
AliasLeukocyte immunoglobulin-like receptor subfamily B member 5,LIR8,CD85C,LIR-8,CD85 antigen-like family member C,Leukocyte immunoglobulin-like receptor 8
BackgroundElisa kits for LILRB5
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

LILRB5 (Leukocyte Immunoglobulin-Like Receptor B5), also known as ILT7 or CD85c, is part of the LILR (leukocyte immunoglobulin-like receptor) family, which plays a pivotal role in immune regulation. The LILR family includes activating and inhibitory receptors expressed on immune cells, primarily myeloid cells. LILRB5, an inhibitory receptor, is encoded within a highly polymorphic region on chromosome 19q13.4. The inhibitory receptors in this family, including LILRB5, interact with major histocompatibility complex (MHC) molecules and other ligands, modulating imm une responses and promoting tolerance, particularly in tissues prone to autoimmune inflammation or where immune homeostasis is critical. LILRB5 expression is seen in monocytes, macrophages, neutrophils, and dendritic cells. Its function is primarily to transmit inhibitory signals that suppress overactive immune responses, which helps protect tissues from damage during prolonged immune activation or chronic inflammatory diseases

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