anti- LILRB5 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
anti- LILRB5 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04778
tested applications
ELISA, WB
Description
May act as receptor for class I MHC antigens.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | leukocyte immunoglobulin-like receptor, subfamily B(with TM and ITIM domains), member 5 |
| Host | Rabbit |
| Reactivity | human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 64kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O75023 |
| Gene ID | 10990 |
| Alias | Leukocyte immunoglobulin-like receptor subfamily B member 5,LIR8,CD85C,LIR-8,CD85 antigen-like family member C,Leukocyte immunoglobulin-like receptor 8 |
| Background | Antibody anti-LILRB5 |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
LILRB5 (Leukocyte Immunoglobulin-Like Receptor B5), also known as ILT7 or CD85c, is part of the LILR (leukocyte immunoglobulin-like receptor) family, which plays a pivotal role in immune regulation. The LILR family includes activating and inhibitory receptors expressed on immune cells, primarily myeloid cells. LILRB5, an inhibitory receptor, is encoded within a highly polymorphic region on chromosome 19q13.4. The inhibitory receptors in this family, including LILRB5, interact with major histocompatibility complex (MHC) molecules and other ligands, modulating imm une responses and promoting tolerance, particularly in tissues prone to autoimmune inflammation or where immune homeostasis is critical. LILRB5 expression is seen in monocytes, macrophages, neutrophils, and dendritic cells. Its function is primarily to transmit inhibitory signals that suppress overactive immune responses, which helps protect tissues from damage during prolonged immune activation or chronic inflammatory diseases
Related Products
Leukocyte Immunoglobulin Like Receptor Subfamily B Member 5 (LILRB5) Antibody
Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With Tm And Itim Domains), Member 5 Antibody is a Rabbit Polyclonal antibody against Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With Tm And Itim Domains), Member 5.
Ver Producto
Leukocyte Immunoglobulin Like Receptor Subfamily B Member 5 (LILRB5) Antibody
LILRB5 Antibody is a Rabbit Polyclonal against LILRB5.
Ver Producto