Human Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) Protein
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Description
Human Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) Protein is a Recombinant Human protein expressed in E. coli.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 1 mg |
| Size 2 | 5 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 1-2 months. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Leukocyte immunoglobulin-like receptor subfamily B member 4,B4,ILT3,LIR5,CD85K,ILT-3,LIR-5,Immunoglobulin-like transcript 3,Leukocyte immunoglobulin-like receptor 5,Monocyte inhibitory receptor HM18 |
| Background | Protein LILRB4 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Leukocyte Immunoglobulin-Like Receptor B4 (LILRB4), also known as CD85K, ILT3, or LIR-5, is an inhibitory receptor expressed mainly on myeloid cells, such as dendritic cells, macrophages, and monocytes. As a member of the leukocyte immunoglobulin-like receptor (LILR) family, it functions primarily to suppress immune responses, maintaining immune homeostasis and preventing overactivation. LILRB4’s immune-modulatory role is particularly crucial in preventing autoimmune reactions and regulating inflammatory responses. Its expression is primarily restricted to cells of the myeloid lineage, making it a key component in myeloid cell function. The gene encoding LILRB4 is located within a cluster of LILR genes on chromosome 19q13.4, close to other LILR genes, which are involved in immune modulation.
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