Human Leukocyte Immunoglobulin Like Receptor A2 (LILRA2) ELISA Kit

715€ (96 tests)
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name
Human Leukocyte Immunoglobulin Like Receptor A2 (LILRA2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx251816
tested applications
ELISA
Description
Human Leukocyte Immunoglobulin Like Receptor A2 (LILRA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leukocyte immunoglobulin-like receptor subfamily A member 2 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | Leukocyte Immunoglobulin Like Receptor A2 (LILRA2) |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 0.156 ng/ml - 10 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q8N149 |
Alias | Leukocyte immunoglobulin-like receptor subfamily A member 2,ILT1,LIR7,CD85H,LIR-7,Immunoglobulin-like transcript 1,Leukocyte immunoglobulin-like receptor 7 |
Background | Elisa kits for LILRA2 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LILRA2, also known as Leukocyte Immunoglobulin-Like Receptor A2 (LILRA2) or CD85h, is a member of the immunoglobulin superfamily and part of the leukocyte immunoglobulin-like receptor (LILR) family. This receptor is encoded by the LILR gene cluster on chromosome 19q13.4, which is home to various immunoglobulin-like receptors involved in immune regulation. LILRA2 plays an activating role in immune response modulation and is predominantly expressed on monocytes, macrophages, and some other leukocyte subsets, such as granulocytes. It is essential in host defense, participating in immune responses to infections and modulating inflammation through cellular signaling pathways. The receptor interacts with a variety of ligands, likely including MHC class I molecules, which allows it to influence both innate and adaptive immunity. The immune-modulating role of LILRA2 makes it an essential subject of study in the context of immune responses and inflammation. Unlike other LILR members that may provide inhibitory signaling, LILRA2 is classified as an activating receptor, generally enhancing immune responses through its interaction with signaling adaptors that contain immunoreceptor tyrosine-based activation motifs (ITAMs). This activating function of LILRA2 contrasts with some members of the LILRB subfamily, which contain immunoreceptor tyrosine-based inhibitory motifs (ITIMs) and thus help suppress immune responses. Research has shown that aberrant expression or dysregulation of LILRA2 can contribute to inflammatory diseases, autoimmunity, and potentially cancer, making it a focal point for therapeutic interventions.
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