Human Leucine Rich Repeat Neuronal Protein 1 (LRRN1) Protein

Background

LRRN1 is a neuronal protein containing leucine-rich repeats that facilitate its interaction with various cellular components in the nervous system. It is widely expressed in the brain, with prominent roles in neural development, synaptic plasticity, and axon guidance. LRRN1 is implicated in cellular adhesion processes critical for neural circuit formation, particularly during embryonic brain development. Additionally, it has been shown to regulate neuronal migration and differentiation by interacting with extracellular matrix components and growth factors. Studies suggest that LRRN1 might play a role in neurodegenerative diseases due to its involvement in maintaining synaptic integrity and its response to neural injury. The multifunctionality of LRRN1 makes it a subject of interest in studies of neural development and neurological disorders.