Human Leucine Rich Repeat Neuronal Protein 1 (LRRN1) Protein

Este producto es parte de LRRN - leucine rich repeat neuronal
Product Graph
234€ (10 µg)

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935106861
info@markelab.com
name
Human Leucine Rich Repeat Neuronal Protein 1 (LRRN1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166156
tested applications
WB, SDS-PAGE

Description

Leucine Rich Repeat Neuronal Protein 1 is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Leucine Rich Repeat Neuronal Protein 1 (LRRN1)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 53.7 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Ser418-Ala631
Tag: N-terminal His tag and GST tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
NLRR1,NLRR-1,FIGLER3,Neuronal leucine-rich repeat protein 1
Background
Protein LRRN1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

LRRN1 is a neuronal protein containing leucine-rich repeats that facilitate its interaction with various cellular components in the nervous system. It is widely expressed in the brain, with prominent roles in neural development, synaptic plasticity, and axon guidance. LRRN1 is implicated in cellular adhesion processes critical for neural circuit formation, particularly during embryonic brain development. Additionally, it has been shown to regulate neuronal migration and differentiation by interacting with extracellular matrix components and growth factors. Studies suggest that LRRN1 might play a role in neurodegenerative diseases due to its involvement in maintaining synaptic integrity and its response to neural injury. The multifunctionality of LRRN1 makes it a subject of interest in studies of neural development and neurological disorders.

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