Human Leucine Rich Repeat Neuronal Protein 1 (LRRN1) Protein

Este producto es parte de LRRN - leucine rich repeat neuronal
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234€ (10 µg)

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935106861
info@markelab.com
name
Human Leucine Rich Repeat Neuronal Protein 1 (LRRN1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166156
tested applications
WB, SDS-PAGE

Description

Leucine Rich Repeat Neuronal Protein 1 is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetLeucine Rich Repeat Neuronal Protein 1 (LRRN1)
HostE. coli
OriginHuman
ConjugationUnconjugated
Observed MWMolecular Weight: Calculated MW: 53.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser418-Ala631 Tag: N-terminal His tag and GST tag
ExpressionRecombinant
Purity> 95%
Size 110 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 5500 µg
FormLyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested ApplicationsWB, SDS-PAGE
BufferPrior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
AvailabilityShipped within 5-7 working days.
StorageStore at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry IceNo
AliasNLRR1,NLRR-1,FIGLER3,Neuronal leucine-rich repeat protein 1
BackgroundProtein LRRN1
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

LRRN1 is a neuronal protein containing leucine-rich repeats that facilitate its interaction with various cellular components in the nervous system. It is widely expressed in the brain, with prominent roles in neural development, synaptic plasticity, and axon guidance. LRRN1 is implicated in cellular adhesion processes critical for neural circuit formation, particularly during embryonic brain development. Additionally, it has been shown to regulate neuronal migration and differentiation by interacting with extracellular matrix components and growth factors. Studies suggest that LRRN1 might play a role in neurodegenerative diseases due to its involvement in maintaining synaptic integrity and its response to neural injury. The multifunctionality of LRRN1 makes it a subject of interest in studies of neural development and neurological disorders.

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