Human Leucine Rich Repeat Containing Protein 4C (LRRC4C) ELISA Kit
715€ (96 tests)
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name
Human Leucine Rich Repeat Containing Protein 4C (LRRC4C) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx388320
tested applications
ELISA
Description
Human Leucine Rich Repeat Containing Protein 4C (LRRC4C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human LRRC4C concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Leucine Rich Repeat Containing Protein 4C (LRRC4C) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9HCJ2 |
| Gene ID | 57689 |
| OMIM | 608817 |
| Alias | LRRC4C, KIAA1580, NGL1,Netrin-G1 ligand ,NGL-1 |
| Background | Elisa kits for LRRC4C |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LRRC4C, or netrin-G ligand 4 (NGL-4), is a member of the leucine-rich repeat protein family involved in synaptic adhesion, axon guidance, and neural circuit formation. It binds to netrin-G proteins at synaptic junctions, facilitating the establishment and stabilization of excitatory synapses in the central nervous system. LRRC4C is highly expressed in the brain, particularly in regions responsible for cognitive and motor functions, where it regulates synaptic plasticity, neuronal migration, and dendritic spine development. Dysregulation of LRRC4C has been linked to neurodevelopmental disorders, such as autism spectrum disorders (ASD) and epilepsy, where disrupted synaptic organization and connectivity lead to impaired brain function. Knockout studies reveal defects in synaptic architecture, altered neuronal communication, and reduced cognitive performance, highlighting its critical role in synaptic development, neural circuit organization, and proper brain function.
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