Human Leucine-rich repeat-containing protein 39 (LRRC39) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Leucine-rich repeat-containing protein 39 (LRRC39) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531391
tested applications
ELISA
Description
Human Leucine-rich repeat-containing protein 39 (LRRC39) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat-containing protein 39 (LRRC39) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Leucine-rich repeat-containing protein 39 (LRRC39) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96DD0 |
| Alias | Myosin-interacting M-band-associated stress-responsive protein,Myomasp |
| Background | Elisa kits for LRRC39 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LRRC39 is a muscle-specific protein localized to the sarcomere where it interacts with structural proteins to maintain sarcomeric integrity and stability it is a critical component of the Z-disk and is involved in the organization of myofilaments during muscle contraction studies indicate LRRC39 plays a role in mechanotransduction and the regulation of myocyte architecture and function mutations in LRRC39 have been associated with dilated cardiomyopathy (DCM) and other forms of cardiac dysfunction where its loss disrupts the sarcomeric structure and compromises cardiac contractility animal models deficient in LRRC39 demonstrate impaired cardiac performance and sarcomeric disarray highlighting its importance in cardiac muscle development and maintenance ongoing research focuses on its interactions with sarcomeric proteins such as titin and its potential as a therapeutic target for inherited and acquired cardiomyopathies
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