Human Leucine-rich repeat-containing protein 39 (LRRC39) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for LRRC39
proveedor
Abbexareference
abx531391Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Leucine-rich repeat-containing protein 39 (LRRC39) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat-containing protein 39 (LRRC39) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
LRRC39 is a muscle-specific protein localized to the sarcomere where it interacts with structural proteins to maintain sarcomeric integrity and stability it is a critical component of the Z-disk and is involved in the organization of myofilaments during muscle contraction studies indicate LRRC39 plays a role in mechanotransduction and the regulation of myocyte architecture and function mutations in LRRC39 have been associated with dilated cardiomyopathy (DCM) and other forms of cardiac dysfunction where its loss disrupts the sarcomeric structure and compromises cardiac contractility animal models deficient in LRRC39 demonstrate impaired cardiac performance and sarcomeric disarray highlighting its importance in cardiac muscle development and maintenance ongoing research focuses on its interactions with sarcomeric proteins such as titin and its potential as a therapeutic target for inherited and acquired cardiomyopathies
Características del producto
category
ELISA Kits
immunogen target
Leucine-rich repeat-containing protein 39 (LRRC39)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
Myosin-interacting M-band-associated stress-responsive protein,Myomasp
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
LRRC39
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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