Human Leucine-rich repeat-containing protein 32 (LRRC32) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for LRRC32
proveedor
Abbexareference
abx531378Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Leucine-rich repeat-containing protein 32 (LRRC32) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat-containing protein 32 (LRRC32) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
LRRC32, also known as glycoprotein A repetitions predominant (GARP), is a membrane protein highly expressed on regulatory T cells (Tregs) and platelets where it plays a critical role in regulating immune tolerance it acts as a receptor for latent TGF-β (transforming growth factor-beta) facilitating its activation and release on the cell surface LRRC32 is crucial for maintaining Treg function and suppressing excessive immune responses studies indicate its involvement in autoimmunity cancer and inflammation where dysregulation of LRRC32-mediated TGF-β signaling contributes to disease progression its role in tumor immunity is particularly notable as it enables tumors to evade immune surveillance by promoting an immunosuppressive microenvironment ongoing research is focused on targeting LRRC32 to modulate Treg activity in diseases such as cancer and autoimmune disorders making it a promising therapeutic candidate
Características del producto
category
ELISA Kits
immunogen target
Leucine-rich repeat-containing protein 32 (LRRC32)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
Garpin,Transforming growth factor beta activator LRRC32,Glycoprotein A repetitions predominant,D11S833E
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
LRRC32
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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