Human Leucine-Rich Repeat-Containing Protein 25 (LRRC25) Protein
299€ (10 µg)
299€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Leucine-Rich Repeat-Containing Protein 25 (LRRC25) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690598
tested applications
SDS-PAGE
Descripción del producto
Human Leucine-Rich Repeat-Containing Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Leucine-Rich Repeat-Containing Protein 25/Monocyte and plasmacytoid-activated protein is produced by our Mammalian expression system and the target gene encoding Leu21-Thr165 is expressed with a 6His tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Especificaciones del producto
| Alias | LRRC25,MAPA,Monocyte and plasmacytoid-activated protein |
| Availability | Shipped within 5-15 working days. |
| Background | Protein LRRC25 |
| Buffer | 20mM PB, 150mM NaCl, pH7.4. |
| Category | Proteins and Peptides |
| Dry Ice | No |
| Expression | Recombinant |
| Form | Lyophilized |
| Host | Human |
| Immunogen Target | Leucine-Rich Repeat-Containing |
| Name | Human Leucine-Rich Repeat-Containing Protein 25 (LRRC25) Protein |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
| Observed MW | Molecular Weight: 16.7 kDa Sequence Fragment: Leu21-Thr165 Tag: C-terminal 6 His tag |
| Origin | Human |
| Price | 299 |
| Provider | Abbexa |
| Purity | > 95% (SDS-PAGE) |
| Reference | abx690598 |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Status | RUO |
| Storage | Store at < -20°C. |
| Tested Applications | SDS-PAGE |
| UniProt ID | Q8N386 |
Descripcion del producto en español
Background en español
LRRC25 is an innate immune receptor predominantly expressed in neutrophils and macrophages where it plays a role in mediating the immune response against infections and cellular stress it functions as a regulator of toll-like receptor (TLR) and nuclear factor-kappa B (NF-κB) signaling pathways essential for pro-inflammatory cytokine production and pathogen clearance studies show that LRRC25 is involved in the recognition of damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs) facilitating the recruitment of immune cells to sites of infection or injury it also participates in the regulation of neutrophil extracellular traps (NETs) which are critical in trapping and neutralizing pathogens dysregulated LRRC25 activity has been linked to chronic inflammatory diseases and autoimmune disorders ongoing research is investigating its potential role as a therapeutic target in modulating hyperactive inflammatory responses and its involvement in the crosstalk between innate and adaptive immunity
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