Human Leucine-rich repeat-containing protein 19 (LRRC19) ELISA Kit

715€ (96 tests)
Este producto es parte de LRRC - Leucine-rich repeat-containing protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Leucine-rich repeat-containing protein 19 (LRRC19) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531354
tested applications
ELISA

Descripción del producto

Human Leucine-rich repeat-containing protein 19 (LRRC19) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat-containing protein 19 (LRRC19) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Especificaciones del producto

AliasLRRC19
Assay DataQuantitative
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
BackgroundElisa kits for LRRC19
CategoryELISA Kits
Detection MethodColorimetric
Dry IceNo
FormLyophilized
Immunogen TargetLeucine-rich repeat-containing protein 19 (LRRC19)
NameHuman Leucine-rich repeat-containing protein 19 (LRRC19) ELISA Kit
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Price715
ProviderAbbexa
ReactivityHuman
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Referenceabx531354
Sample TypeTissue homogenates, cell lysates and other biological fluids.
Size 196 tests
StatusRUO
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Test Range0.156 ng/ml - 10 ng/ml
Tested ApplicationsELISA
UniProt IDQ9H756

Descripcion del producto en español

Background en español

LRRC19 is a membrane protein implicated in innate immune signaling where it functions as a pattern recognition receptor (PRR) involved in the detection of microbial components it directly activates downstream pathways such as nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) cascades essential for initiating inflammatory responses LRRC19 is predominantly expressed in dendritic cells and macrophages where it contributes to pathogen recognition and the activation of adaptive immunity by promoting antigen presentation studies suggest LRRC19 plays a critical role in the regulation of pro-inflammatory cytokine production and may act as a mediator in host-pathogen interactions its dysregulation has been associated with chronic inflammatory diseases and autoimmune conditions such as rheumatoid arthritis and inflammatory bowel disease ongoing research is exploring its potential as a target for modulating inflammatory responses and its involvement in maintaining immune homeostasis during infections and sterile inflammation

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