Human Killer cell immunoglobulin-like receptor 3DL3 (KIR3DL3) ELISA Kit

Este producto es parte de KIR3DL - Killer cell immunoglobulin-like receptor 3DL
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Killer cell immunoglobulin-like receptor 3DL3 (KIR3DL3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx529950
tested applications
ELISA

Description

Human Killer cell immunoglobulin-like receptor 3DL3 (KIR3DL3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Killer cell immunoglobulin-like receptor 3DL3 (KIR3DL3) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetKiller cell immunoglobulin-like receptor 3DL3 (KIR3DL3)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ8N743
OMIM610095
AliasKIR44,KIRC1,CD158Z,KIR3DL7,KIR2DL5B,CD158 antigen-like family member Z,Killer cell inhibitory receptor 1
BackgroundElisa kits for KIR3DL3
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Killer Cell Immunoglobulin-Like Receptor 3DL3 (KIR3DL3), another member of the KIR family, is expressed primarily on NK cells and a subset of T cells, contributing to the modulation of innate and adaptive immune responses. While less well-characterized than other KIR family members, KIR3DL3 is thought to provide inhibitory signals upon binding to its ligands, which include specific HLA class I molecules. Its expression and function are tightly regulated, and genetic studies suggest a role in immune system variability, with potential implications in transplantation immunology and disease susceptibility. Emerging research is exploring the relevance of KIR3DL3 in the context of immune evasion by tumors and infectious agents, emphasizing its potential as a target for enhancing immune responses in therapeutic settings.

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