Human Killer cell immunoglobulin-like receptor 3DL2 (KIR3DL2) Protein
234€ (1 µg)
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935106861
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name
Human Killer cell immunoglobulin-like receptor 3DL2 (KIR3DL2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680101
tested applications
SDS-PAGE
Description
Human Killer cell immunoglobulin-like receptor 3DL2 (KIR3DL2) Protein is a recombinant protein produced in Sf9, Baculovirus cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Killer cell immunoglobulin-like receptor 3DL2 (KIR3DL2) |
| Host | Insect |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE) |
| Size 1 | 1 µg |
| Size 2 | 5 µg |
| Size 3 | 50 µg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | CD158 antigen-like family member K,Natural killer-associated transcript 4,NKAT-4,p70 natural killer cell receptor clone CL-5,3DL2,CD158K,NKAT4B,KIR-3DL2 |
| Background | Protein KIR3DL2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Killer Cell Immunoglobulin-Like Receptor 3DL2 (KIR3DL2) is a member of the KIR family of receptors expressed predominantly on natural killer (NK) cells and subsets of T cells, playing a significant role in immune system regulation and surveillance. This receptor specifically interacts with HLA class I molecules, with a preference for HLA-A3 and HLA-A11 alleles, delivering inhibitory signals that modulate NK cell cytotoxicity and cytokine production. KIR3DL2 polymorphisms and expression levels have been implicated in susceptibility to autoimmune diseases such as ankylosing spondylitis and certain infections, demonstrating its critical role in balancing immune activation and tolerance. Recent studies highlight the involvement of KIR3DL2 in cancer, particularly in Hodgkin’s lymphoma, where it may serve as a therapeutic target for novel immunotherapies. Through its inhibitory signaling and interaction with diverse HLA ligands, KIR3DL2 ensures immune homeostasis while also influencing outcomes in transplantation and disease progression.
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