Human Killer cell immunoglobulin-like receptor 3DL2 (KIR3DL2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits KIR3DL2
proveedor
Abbexareference
abx529949Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Killer cell immunoglobulin-like receptor 3DL2 (KIR3DL2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Killer cell immunoglobulin-like receptor 3DL2 (KIR3DL2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Killer Cell Immunoglobulin-Like Receptor 3DL2 (KIR3DL2) is a member of the KIR family of receptors expressed predominantly on natural killer (NK) cells and subsets of T cells, playing a significant role in immune system regulation and surveillance. This receptor specifically interacts with HLA class I molecules, with a preference for HLA-A3 and HLA-A11 alleles, delivering inhibitory signals that modulate NK cell cytotoxicity and cytokine production. KIR3DL2 polymorphisms and expression levels have been implicated in susceptibility to autoimmune diseases such as ankylosing spondylitis and certain infections, demonstrating its critical role in balancing immune activation and tolerance. Recent studies highlight the involvement of KIR3DL2 in cancer, particularly in Hodgkin’s lymphoma, where it may serve as a therapeutic target for novel immunotherapies. Through its inhibitory signaling and interaction with diverse HLA ligands, KIR3DL2 ensures immune homeostasis while also influencing outcomes in transplantation and disease progression.
Características del producto
category
ELISA Kits
immunogen target
Killer cell immunoglobulin-like receptor 3DL2 (KIR3DL2)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
CD158 antigen-like family member K,Natural killer-associated transcript 4,NKAT-4,p70 natural killer cell receptor clone CL-5,3DL2,CD158K,NKAT4B,KIR-3DL2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
KIR3DL2
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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