Human Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3) ELISA Kit

Este producto es parte de KIR2DL3 - Killer cell immunoglobulin-like receptor 2DL3
Human Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits KIR2DL3

proveedor

Abbexa

reference

abx388160

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human KIR2DL3 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

KIR2DL3 is an inhibitory receptor that is part of the killer cell immunoglobulin-like receptor (KIR) family, which is primarily expressed on natural killer (NK) cells and some T-cell subsets. This receptor plays a pivotal role in immune surveillance and modulation by binding to specific HLA class I molecules, particularly HLA-C alleles, on potential target cells. KIR2DL3 recognizes HLA-C1 (characterized by an asparagine at position 80), which is different from HLA-C2 (lysine at position 80) recognized by related receptors like KIR2DL1. By binding to HLA-C1, KIR2DL3 sends inhibitory signals that regulate NK cell cytotoxicity, promoting immune tolerance and minimizing the risk of autoimmunity. The KIR genes, including KIR2DL3, are located on chromosome 19q13.4 in a highly polymorphic region known as the leukocyte receptor complex (LRC). Genetic variability within this complex, particularly in the KIR2DL3 and its HLA-C ligands, contributes to diversity in immune response among individuals. Variants in KIR2DL3 and other KIR genes are associated with differential susceptibility to diseases, including autoimmune disorders, viral infections, and cancers.

Características del producto

category

ELISA Kits


immunogen target

Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.06 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

CD158 antigen-like family member B2,KIR-023GB,Killer inhibitory receptor cl 2-3,NKAT2a,NKAT2b,GL183,CD158b,KIR2DL


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

KIR2DL3


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

anti- KIR2DL3 antibody

anti- KIR2DL3 antibody

proveedor

FineTest

reference

FNab04581

Tested Applications

ELISA, WB

reactivity

human

status

RUO

clonality

polyclonal

Receptor on natural killer(NK) cells for HLA-C alleles(HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells ...

Precio a consultar

Ver más

Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3) Antibody

Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3) Antibody

proveedor

Abbexa

reference

abx001423

Tested Applications

WB, IF/ICC

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

KIR2DL3 Antibody is a Rabbit Polyclonal antibody against KIR2DL3. Killer cell immunoglobulin-like receptors (KIRs) are t...

175€ (20 µl)

Ver más

Human Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3) Protein

Human Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3) Protein

proveedor

Abbexa

reference

abx067649

Tested Applications

WB, SDS-PAGE

status

RUO

Recombinant Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3) is a recombinant Human protein produced in E. coli u...

237.5€ (10 µg)

Ver más