Human Junction Adhesion Molecule Like (JAML) Protein

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Human JAML Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human JAML (NP_001091996.1) extracellular domain (Met 1-Leu 275) was fused with a polyhistidine tag at the C-terminus.
Documents del producto
Product specifications
Category | Proteins and Peptides |
Immunogen Target | JAML |
Host | HEK293 cells |
Origin | Human |
Observed MW | Molecular Weight: 30.5 kDa Sequence Fragment: Met1-Leu275 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
Expression | Recombinant |
Purity | > 90% (SDS-PAGE) |
Size 1 | 100 µg |
Form | |
Tested Applications | SDS-PAGE |
Buffer | Lyophilized from sterile PBS, pH 7.4. |
Availability | Shipped within 5-15 working days. |
Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
NCBI Accession | NP_001091996.1 |
Alias | AMICA,Gm638,AMICA1,CREA7-1,CREA7-4,Dendritic cell-specific protein,Adhesion molecule interacting with CXADR antigen 1 |
Background | Protein JAML |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Junctional adhesion molecule-like (JAML) protein is part of the immunoglobulin superfamily, which encompasses a wide range of proteins involved in cell-cell adhesion, immune responses, and cellular signaling. JAML is known for its critical role in the immune system, particularly in the regulation of immune cell interactions and functions. The protein is expressed predominantly on epithelial cells and various immune cells, including neutrophils and certain T-cell subsets, where it contributes to immune surveillance and tissue homeostasis.
Related Products

anti- JAML antibody
Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.
Ver Producto
Recombinant Human JAML
Ver Producto
Junction Adhesion Molecule Like (JAML) Antibody
Adhesion Molecule, Interacts With Cxadr Antigen 1 Antibody is a Rabbit Polyclonal antibody against Adhesion Molecule, Interacts With Cxadr Antigen 1.
Ver Producto