Human Interleukin 7 (IL7) Protein
494€ (10 µg)
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name
Human Interleukin 7 (IL7) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx670174
tested applications
ELISA, WB
Description
Human Interleukin 7 (IL7) Protein is a Recombinant protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 7 (IL7) |
| Host | E. coli |
| Recommended Dilution | ELISA: 0.2-0.4 ng/well, WB: 1.5-3.0 ng/lane, Functional Assays: 0.1-10 ng/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: 17.5 kDa Sequence Fragment: Full length (153 AA.) |
| Purity | > 98% (SDS-PAGE and HPLC) |
| Size 1 | 10 µg |
| Form | Lyophilized Reconstitute in 0.1 ml distilled water to obtain a protein concentration of 0.1 mg/ml. For extended storage, it is recommended to add 0.1% BSA. Gently mix after reconstitution. |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 10 mM Acetic Acid. Does not contain preservatives. |
| Availability | Shipped within 3-7 working days. |
| Storage | Store lyophilized at -20 °C. After reconstitution, aliquot and store undiluted at -20 °C for up to 3 months. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P13232 |
| Alias | IL-7 |
| Background | Protein IL7 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin-7 (IL7) is a critical cytokine primarily involved in the development, survival, and homeostasis of immune cells, particularly T cells and B cells. It plays an essential role in lymphopoiesis, ensuring the proper function and maintenance of the adaptive immune system. IL-7 is produced mainly by stromal cells in the bone marrow and thymus, but it is also secreted by epithelial cells in other tissues, such as the intestines, liver, and skin. Unlike many cytokines, IL-7 is not produced by immune cells themselves but acts as a growth factor necessary for immune cell survival and proliferation. IL-7 is vital for the survival of naïve and memory T cells, supporting the homeostasis of these populations throughout life. It also supports the early stages of B cell development in the bone marrow and ensures the development of a healthy and functional immune system. IL-7’s function in maintaining T cell homeostasis and supporting immune recovery has made it a target of interest in immunotherapy, particularly for treating immune deficiencies, enhancing cancer immunotherapy, and facilitating immune reconstitution in HIV patients.
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