Human Interleukin 6 Receptor (IL6R) ELISA Kit

Este producto es parte de IL6R - Interleukin 6 Receptor
Human Interleukin 6 Receptor (IL6R) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

493.75€ (96 tests)

Elisa Kits IL6R

proveedor

Abbexa

reference

abx253572

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Interleukin 6 Receptor (IL6R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Interleukin 6 Receptor (IL6R) concentrations in serum, plasma and other biological fluids.


Background

IL6R is a key component of the interleukin-6 (IL6) signaling pathway, consisting of a membrane-bound and soluble form (sIL6R), which binds IL6 and mediates downstream effects via the gp130 co-receptor This interaction activates the JAK/STAT3, MAPK, and PI3K/AKT pathways, regulating immune responses, inflammation, and hematopoiesis IL6R signaling is critical in acute-phase responses, B cell maturation, and T cell proliferation Dysregulation of IL6R activity is implicated in chronic inflammatory diseases such as rheumatoid arthritis, inflammatory bowel disease, and systemic lupus erythematosus (SLE) In cancer, IL6R signaling supports tumor progression, angiogenesis, and immune evasion Therapeutic targeting of IL6R, such as with tocilizumab, is effective in reducing inflammation and cytokine storm in conditions like COVID-19, autoimmune disorders, and hematological malignancies

Características del producto

category

ELISA Kits


immunogen target

Interleukin 6 Receptor (IL6R)


reactivity

Human


test range

31.2 pg/ml - 2000 pg/ml


sensitivity

18.8 pg/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Serum,Plasma,Other biological fluids


size 1

96 tests


alias

IL6Q,gp80,CD126,HIES5,IL-6R,IL6RA,IL6RQ,IL-1Ra,IL-6RA,IL6QTL,IL-6R-1,L-6R-Alpha,IL-6Rα


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

IL6R


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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