Human Interleukin 26 (IL26) Protein
4446€ (1 mg)
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name
Human Interleukin 26 (IL26) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655726
tested applications
WB, SDS-PAGE
Description
Human Interleukin 26 (IL26) Protein (Active) is an Active Recombinant Human protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 26 (IL26) |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 1 mg |
| Size 2 | 5 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 1-2 months. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | AK155,IL-26,Protein AK155 |
| Background | Protein IL26 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin 26 (IL26) is a member of the IL-10 cytokine family and is notable for its dual role in both immune modulation and antimicrobial defense. It is predominantly expressed by activated T cells, especially Th17 cells, as well as NK cells and some monocytes. IL-26 has been primarily studied in the context of chronic inflammation and is implicated in the pathogenesis of various autoimmune conditions, particularly rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and other chronic inflammatory diseases. IL-26 plays a unique role within the immune system by acting as both a cytokine and a host-defense peptide. As a cytokine, it helps orchestrate immune responses, particularly those involving Th17 cells, and as an antimicrobial peptide, it exhibits direct bactericidal properties. Its ability to bind and disrupt bacterial membranes marks IL-26 as part of the innate immune defense against pathogens.
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