Human Interleukin 25 (IL25) Protein

Este producto es parte de IL25 - interleukin 25
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221€ (10 µg)

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935106861
info@markelab.com
name
Human Interleukin 25 (IL25) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067512
tested applications
WB, SDS-PAGE

Description

Recombinant Interleukin 25 (IL25) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetInterleukin 25 (IL25)
HostE. coli
OriginHuman
ConjugationUnconjugated
Observed MWMolecular Weight: Calculated MW: 18.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met28-Gly177 Tag: N-terminal His tag
ExpressionRecombinant
Purity> 95%
Size 110 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 5500 µg
FormLyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested ApplicationsWB, SDS-PAGE
BufferPrior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
AvailabilityShipped within 5-12 working days.
StorageStore at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ9H293
AliasIL17E,Interleukin-17E
BackgroundProtein IL25
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interleukin 25 (IL25), also known as IL-17E, is a cytokine that belongs to the IL-17 cytokine family. It is primarily known for its role in the promotion of type 2 immune responses, which are typically associated with allergic inflammation and parasite defense. IL-25 is produced by several cell types, including epithelial cells, T helper type 2 (Th2) cells, eosinophils, mast cells, and macrophages. As a key regulator of Th2 immunity, IL-25 is involved in the induction of cytokines such as IL-4, IL-5, and IL-13, which drive immune responses linked to asthma, allergic rhinitis, and helminth infections. The role of IL-25 extends beyond its involvement in type 2 immune responses, as it has been implicated in tissue repair, mucosal barrier integrity, and homeostasis.

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