Human Interleukin 20 (IL20) Protein

494€ (50 µg)
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935106861
info@markelab.com
name
Human Interleukin 20 (IL20) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx651390
tested applications
WB, SDS-PAGE
Description
Interleukin 20 (IL20) Protein (Active) is an active protein from Human.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Interleukin 20 (IL20) |
Origin | Human |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 21.2 kDa Observed MW: 21 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu25-Glu176 Tag: N-terminal His tag |
Purity | > 90% |
Size 1 | 50 µg |
Size 2 | 100 µg |
Size 3 | 200 µg |
Size 4 | 500 µg |
Size 5 | 1 mg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9NYY1 |
Alias | IL-20,IL10D,ZCYTO10,Cytokine Zcyto10 |
Background | Protein IL20 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin 20 (IL20) is a member of the IL-10 cytokine family, which includes structurally related cytokines like IL-19, IL-22, IL-24, and IL-26. These cytokines share common biological functions in regulating immune responses, inflammation, and tissue homeostasis. IL-20, in particular, is predominantly associated with the modulation of skin, lung, and other epithelial tissues, where it exerts its effects on inflammation, tissue repair, and the innate immune response. IL-20 is produced by various cell types, including monocytes, keratinocytes, endothelial cells, and fibroblasts. Its expression is induced by pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-α, particularly in tissues experiencing inflammation or injury. IL-20 acts primarily on epithelial and immune cells to regulate tissue homeostasis and inflammation, making it an important mediator in diseases like psoriasis, rheumatoid arthritis, and pulmonary inflammation.
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