Human Interleukin 13 Receptor Alpha 2 (IL13Ra2) Protein
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935106861
info@markelab.com
Precio
260€ (10 µg)
Protein IL13RA2
proveedor
Abbexareference
abx067446Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Interleukin 13 Receptor Alpha 2 (IL13Ra2) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
Interleukin-13 receptor subunit alpha-2 (IL13RA2) is a protein encoded by the IL13RA2 gene, which functions as part of the immune system’s response to inflammation and certain immune-regulatory mechanisms. IL13RA2 is closely related to interleukin-13 receptor subunit alpha-1 (IL13RA1), both of which bind to the cytokine interleukin-13 (IL-13). However, IL13RA2 is distinctive in that it acts as a “decoy” receptor, binding IL-13 with high affinity but not actively initiating intracellular signaling, thereby modulating the effects of IL-13 on immune responses. IL13RA2 has roles in regulating allergic reactions and fibrotic processes and is often upregulated in various pathological conditions, including certain cancers. The protein's interactions with IL-13 have implications for tissue remodeling, fibrosis, and immune regulation, making it an important target in the fields of immunology, oncology, and fibrosis research.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Interleukin 13 Receptor Alpha 2 (IL13Ra2)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 12.5 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro238-Glu334 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
IL13RA2
dry ice
No
availability
Shipped within 5-12 working days.
alias
IL-13 receptor subunit alpha-2,CT19,IL-13R,IL13BP,CD213A2,Interleukin-13-binding protein
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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