Human Interleukin 10 Receptor Subunit Beta (IL10RB) Protein

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Description
Human Interleukin 10 Receptor Subunit Beta (IL10RB) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
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Product specifications
Category | Proteins and Peptides |
Immunogen Target | Interleukin 10 Receptor Subunit Beta (IL10RB) |
Host | Mammalian cells |
Origin | Human |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 51.82 kDa Sequence Fragment: Met1-Ser220 Tag: C-terminal Fc tag |
Expression | Recombinant |
Purity | > 90% (SDS-PAGE) |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Liquid |
Tested Applications | ELISA, WB, SDS-PAGE |
Buffer | 0.01 M PBS, pH 7.4. |
Availability | Shipped within 5-12 working days. |
Storage | Store at 2-8 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
Dry Ice | No |
UniProt ID | Q08334 |
Alias | CRFB4,Cytokine receptor family 2 member 4,CRF2-4,Interleukin-10 receptor subunit 2,IL-10R subunit 2,IL-10R2 |
Background | Protein IL10RB |
Note | This product is for research use only. This product is shipped with ice packs. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes(ISG), which contribute to the antiviral state.
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Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes(ISG), which contribute to the antiviral state.
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