Human Interferon Omega (IFNw) Protein

559€ (50 µg)
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name
Human Interferon Omega (IFNw) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655698
tested applications
WB, SDS-PAGE
Description
Human Interferon Omega (IFNw) Protein (Active) is an Active recombinant Human protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interferon Omega (IFNw) |
| Assay Type | Activity: Active Sequence Fragment: Please enquire. Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | Interferon alpha-II-1 |
| Background | Protein IFNW1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
Interferon Omega 1 (IFNW1) is a type I interferon that belongs to the family of interferons known for their critical roles in antiviral defense, immune regulation, and cell growth inhibition. IFNW1 is predominantly produced by leukocytes in response to viral infections and other immune stimuli. This cytokine binds to the type I interferon receptor (IFNAR), initiating a signaling cascade through the JAK-STAT pathway. This activation leads to the transcription of interferon-stimulated genes (ISGs), which encode proteins that inhibit viral replication, enhance antigen presentation, and activate immune cells such as natural killer cells and macrophages. IFNW1 has a similar but distinct activity profile compared to other type I interferons, such as IFN-alpha and IFN-beta, with potential applications in treating viral infections and certain malignancies. It is being explored in therapeutic contexts, including its use as an immunomodulatory agent in chronic viral infections and autoimmune disorders. Elevated levels of IFNW1 are associated with heightened immune activity, and its therapeutic modulation could provide benefits in diseases with dysregulated immune responses.
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