Human Interferon Omega (IFNw) Protein

Product specifications

Proteins and Peptides

Interferon Omega (IFNw)

Human

Unconjugated

Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Please enquire.
Tag: N-terminal His tag

Recombinant

> 90%

1 mg

5 mg

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.

WB, SDS-PAGE

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.

Shipped within 1-2 months.

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

No

Interferon alpha-II-1

Protein IFNW1

RUO

This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interferon Omega 1 (IFNW1) is a type I interferon that belongs to the family of interferons known for their critical roles in antiviral defense, immune regulation, and cell growth inhibition. IFNW1 is predominantly produced by leukocytes in response to viral infections and other immune stimuli. This cytokine binds to the type I interferon receptor (IFNAR), initiating a signaling cascade through the JAK-STAT pathway. This activation leads to the transcription of interferon-stimulated genes (ISGs), which encode proteins that inhibit viral replication, enhance antigen presentation, and activate immune cells such as natural killer cells and macrophages. IFNW1 has a similar but distinct activity profile compared to other type I interferons, such as IFN-alpha and IFN-beta, with potential applications in treating viral infections and certain malignancies. It is being explored in therapeutic contexts, including its use as an immunomodulatory agent in chronic viral infections and autoimmune disorders. Elevated levels of IFNW1 are associated with heightened immune activity, and its therapeutic modulation could provide benefits in diseases with dysregulated immune responses.

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