Human Interferon Omega (IFNw) Protein

Este producto es parte de IFNW1 - interferon omega 1
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559€ (50 µg)

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935106861
info@markelab.com
name
Human Interferon Omega (IFNw) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655698
tested applications
WB, SDS-PAGE

Description

Human Interferon Omega (IFNw) Protein (Active) is an Active recombinant Human protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Interferon Omega (IFNw)
Assay Type
Activity: Active
Sequence Fragment: Please enquire.
Tag: N-terminal His tag
Origin
Human
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 90%
Size 1
50 µg
Size 2
100 µg
Size 3
200 µg
Size 4
500 µg
Size 5
1 mg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
Alias
Interferon alpha-II-1
Background
Protein IFNW1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Descripción

Interferon Omega 1 (IFNW1) is a type I interferon that belongs to the family of interferons known for their critical roles in antiviral defense, immune regulation, and cell growth inhibition. IFNW1 is predominantly produced by leukocytes in response to viral infections and other immune stimuli. This cytokine binds to the type I interferon receptor (IFNAR), initiating a signaling cascade through the JAK-STAT pathway. This activation leads to the transcription of interferon-stimulated genes (ISGs), which encode proteins that inhibit viral replication, enhance antigen presentation, and activate immune cells such as natural killer cells and macrophages. IFNW1 has a similar but distinct activity profile compared to other type I interferons, such as IFN-alpha and IFN-beta, with potential applications in treating viral infections and certain malignancies. It is being explored in therapeutic contexts, including its use as an immunomodulatory agent in chronic viral infections and autoimmune disorders. Elevated levels of IFNW1 are associated with heightened immune activity, and its therapeutic modulation could provide benefits in diseases with dysregulated immune responses.

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