Human Interferon Lambda-1 (IFNL1) Protein

Product specifications

Proteins and Peptides

HEK293 cells

Human

Molecular Weight: Calculated MW: 22 kDa  Observed MW (SDS-PAGE): 28-35 kDa
Sequence Fragment: Met1-Thr200
Tag: N-terminal 10 His tag

Recombinant

>95% (SDS-PAGE)

20 µg

100 µg

Lyophilized Reconstitute in sterile H2O. Do not vortex.

SDS-PAGE

Prior to lyophilization: PBS, pH 7.4, 5% Trehalose, 5% Mannitol, 0.01% Tween-80.

Shipped within 5-15 working days.

Store lyophilized between -20 °C and -80 °C.

No

Q8IU54

282618

6743

IL29,IL-29,IFN-lambda-1,Cytokine Zcyto21

Protein IFNL1

RUO

This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interferon Lambda 1 (IFNL1), also known as IL-29, is a member of the Type III interferon family, which includes IFNL1, IFNL2 (IL-28A), and IFNL3 (IL-28B), and more recently discovered IFNL4. These cytokines are involved in antiviral immunity and have significant overlap in function with Type I interferons (such as IFN-α and IFN-β), but with distinct cellular targeting. IFNL1 plays a key role in the innate immune response, especially in protecting epithelial barriers, such as those found in the lungs, intestines, and liver, from viral infections. Unlike Type I interferons, which have broad activity across multiple cell types, Type III interferons like IFNL1 act primarily on cells that express the interferon lambda receptor (IFNLR1), which is most commonly found on epithelial cells and some immune cells like dendritic cells. This targeted action is thought to provide a more localized antiviral defense while minimizing the systemic inflammatory responses often seen with Type I interferons.

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