IFNL1 antibody
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935106861
info@markelab.com
name
IFNL1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04265
tested applications
ELISA, WB
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | interleukin 29(interferon, lambda 1) (IFNL1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:5000-1:20000 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 6G0 |
| Observed MW | 22kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8IU54 |
| Gene ID | 282618 |
| Alias | IL29,IL-29,IFN-lambda-1,Cytokine Zcyto21 |
| Background | Antibody anti-IFNL1 |
| Status | RUO |
| Note | Mol. Weight 22 kDa |
Interferon Lambda 1 (IFNL1), also known as IL-29, is a member of the Type III interferon family, which includes IFNL1, IFNL2 (IL-28A), and IFNL3 (IL-28B), and more recently discovered IFNL4. These cytokines are involved in antiviral immunity and have significant overlap in function with Type I interferons (such as IFN-α and IFN-β), but with distinct cellular targeting. IFNL1 plays a key role in the innate immune response, especially in protecting epithelial barriers, such as those found in the lungs, intestines, and liver, from viral infections. Unlike Type I interferons, which have broad activity across multiple cell types, Type III interferons like IFNL1 act primarily on cells that express the interferon lambda receptor (IFNLR1), which is most commonly found on epithelial cells and some immune cells like dendritic cells. This targeted action is thought to provide a more localized antiviral defense while minimizing the systemic inflammatory responses often seen with Type I interferons.
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