Human Interferon Alpha 3 (IFNa3) Protein

Este producto es parte de IFNA4 - interferon alpha 4
Product Graph
4303€ (1 mg)

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935106861
info@markelab.com
name
Human Interferon Alpha 3 (IFNa3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655685
tested applications
WB, SDS-PAGE

Description

Human Interferon Alpha 3 (IFNa3) Protein (Active) is an Active Recombinant Human protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Interferon Alpha 3 (IFNa3)
Origin
Human
Conjugation
Unconjugated
Observed MW
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Please enquire.
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
1 mg
Size 2
5 mg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 1-2 months.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
INFA4,IFN-alpha4a,IFN-alpha-4,Interferon alpha-4B,Interferon alpha-76,Interferon alpha-M1
Background
Protein IFNA4
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interferon Alpha 4 (IFNA4) is another member of the type I interferon family that contributes to the antiviral immune response. While less characterized than IFNA1 and IFNA2, IFNA4 exhibits similar functional properties, including activation of the IFNAR pathway and induction of interferon-stimulated genes that inhibit viral replication and modulate the immune response. Studies suggest that IFNA4 may have unique regulatory functions or tissue-specific roles within the broader interferon response. Its expression and functional significance may vary depending on the type of infection or immune challenge. As with other type I interferons, IFNA4's dysregulation could contribute to autoimmune conditions, and understanding its precise role in health and disease remains an area of ongoing research.

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