Human Interferon Alpha 14 (IFNA14) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Interferon Alpha 14 (IFNA14) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx251822
tested applications
ELISA
Description
Human Interferon Alpha 14 (IFNA14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Interferon alpha-14 concentrations in serum, plasma and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Interferon Alpha 14 (IFNA14) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 15.6 ng/ml - 1000 ng/ml |
| Sensitivity | < 9.80 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P01570 |
| Alias | LEIF2H,IFN-alphaH,FN-alpha-14,Interferon lambda-2-H,Interferon alpha-H,LeIF H |
| Background | Elisa kits for IFNA14 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Interferon Alpha 14 (IFNA14) is an integral member of the type I interferon family and contributes significantly to the immune system's antiviral defense. Like other alpha interferons, IFNA14 is secreted by plasmacytoid dendritic cells, monocytes, and other immune cells in response to viral infections, particularly during the early stages. Once released, IFNA14 binds to the interferon alpha/beta receptor (IFNAR) on the surface of various cell types, initiating a signaling cascade through the JAK-STAT pathway. This leads to the transcription of numerous interferon-stimulated genes, which are crucial for antiviral activities, such as halting viral replication, promoting apoptosis in infected cells, and enhancing antigen presentation to T cells. Furthermore, IFNA14 aids in the activation and proliferation of natural killer (NK) cells and cytotoxic T lymphocytes, strengthening the immune system's ability to target and eliminate infected cells. Its specific role within the alpha interferon family may involve unique expression patterns or targeted immune functions, though further research is needed to fully delineate its contributions to immunity and potential clinical applications.
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