Human Intercellular Adhesion Molecule 2 / CD102 (ICAM2) Protein
169€ (10 µg)
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935106861
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name
Human Intercellular Adhesion Molecule 2 / CD102 (ICAM2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx653904
tested applications
WB, SDS-PAGE
Description
Human Intercellular Adhesion Molecule 2 (ICAM2) Protein is a Recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Intercellular Adhesion Molecule 2 / CD102 (ICAM2) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 27.3 kDa Observed MW: 28 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Lys34-Ile247 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Intercellular adhesion molecule 2,CD102,ICAM-2 |
| Background | Protein ICAM2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Intercellular adhesion molecule 2 (ICAM2) is a member of the immunoglobulin superfamily and plays an essential role in immune cell trafficking, endothelial integrity, and cell signaling. ICAM-2 is encoded by the ICAM2 gene and, along with other intercellular adhesion molecules, serves as a ligand for leukocyte integrins such as LFA-1 (lymphocyte function-associated antigen-1), facilitating the adhesion and transmigration of leukocytes across endothelial cells. It is broadly expressed on endothelial cells, leukocytes, and various other cell types. ICAM-2 is involved in vascular and immune system homeostasis, with roles extending to inflammation, cancer, and neurological functions. Unlike ICAM-1, which is inducible by inflammatory cytokines, ICAM-2 is constitutively expressed but has been found to increase in certain pathophysiological conditions, especially involving endothelial activation. The stable presence of ICAM-2 on endothelial cells makes it significant for lymphocyte recirculation and endothelial-leukocyte interactions, aiding immune surveillance and response to pathogens.
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